April 4, 2017 / 12:07 PM / a year ago

BRIEF-Uniqure publishes data demonstrating wide distribution of AAV5 in the central nervous system

April 4 (Reuters) - Uniqure NV:

* Uniqure NV -publication in gene therapy of data demonstrating widespread transduction in cns following direct injection of co's aav5 vector in large animal model

* Uniqure - expects to file an investigational new drug (ind) application for amt-130 in 2018

* Uniqure - varying doses of aav5 achieved predictable transduction of connected areas of brain

* Uniqure - data shows AAV5 is an effective vector for central nervous system and has potential for treatment of a wide range of neurological pathologies

* Uniqure - method of injection used was found to result in very controlled, accurate administration with no adverse events observed in non-human primates Source text for Eikon: Further company coverage:

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