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* FTSE 100 flat, FTSE 250 adds 0.1%
June 4 (Reuters) - British shares struggled for direction on Friday as investors stayed away from making big bets ahead of domestic construction activity data and U.S. jobs numbers, while airline stocks came under pressure on tightening of travel restrictions.
The blue-chip FTSE 100 index was flat. British airways owner IAG slipped 2% after Britain removed Portugal from its quarantine-free travel list, and added seven more countries to its red list.
Other airlines including Ryanair Holdings, Wizz Air and EasyJet fell between 1% and 2.4%.
The domestically focused mid-cap FTSE 250 index inched 0.1% higher.
Asian shares tracked Wall Street lower as signs of a firming U.S. economy stoked worries about higher inflation and an earlier withdrawal of Federal Reserve stimulus.
All eyes are now on the U.S. non-farm payrolls report for May due later in the day.
Among other stock, Reckitt Benckiser Group gained 1.3% after HSBC raised its price target on the stock. (Reporting by Devik Jain in Bengaluru; Editing by Subhranshu Sahu)