(Adds Asian shares, U.S. stock futures, oil prices)
* Asian stock markets : tmsnrt.rs/2zpUAr4
* Treasuries rally, 2-year yields below Fed rates
* Dollar on defensive vs yen, near 9-mth lows
* Safe-haven gold around 6-1/2 month peak
By Swati Pandey
SYDNEY, Jan 4 (Reuters) - Global markets were on edge on Friday as dire U.S. economic data slammed Wall Street and pushed investors to bet the Federal Reserve could reverse its policy tightening before the end of this year.
U.S. stock futures slipped in early Asian trade with E-Minis for the S&P 500 off 0.3 percent.
Japan's Nikkei spiralled about 3.6 percent lower, led by a spike in the yen. Australian shares skidded over 1 percent, dragging MSCI's index of Asia-Pacific shares outside Japan 0.2 percent lower to near two-month lows.
Fears the Sino-U.S. trade battle would drag down world growth roiled risk-sensitive assets in 2018, driving a surge in volatility and sending major stock markets deep into the red.
Those worries found some basis this week with Thursday's disappointing survey data from the Institute for Supply Management (ISM) showing U.S. factory activity slowed more than expected in December.
That followed Apple Inc's announcement on Wednesday that it had cut its revenue forecast for the first time in nearly 12 years, blaming weaker iPhone sales in China. Its shares crashed nearly 10 percent overnight.
The dismal ISM report drove investors to the safety of bonds. Yields on the two-year Treasuries sank below 2.4 percent to reach parity with the federal funds effective rate for the first time since 2008.
Three- and five-year yields were even lower, an inversion that has sometimes heralded recessions in the past. Yields on 10-year benchmark paper dropped to 2.55 percent, a staggering turnaround from the highs of 3.25 percent seen as recently as November.
The falls kept the dollar on the defensive. The greenback plumbed a more than nine-month low of 105.25 against the safe-haven yen on Thursday, driven by technical factors amid thin holiday trade.
It has fallen more than 2 percent so far this week, the biggest weekly loss since last February, and was last at 107.675.
"The ISM manufacturing index tumbled more than five points. A drop of this magnitude has only been seen four times since 1980, three of which the economy was in the midst of recession," said Michelle Girard, U.S. economist at RBS.
"The ISM has a long track-record and big moves often prove to be meaningful. The December drop therefore gives pause, even to us economic optimists," Girard added.
"Now...a closely-watched indicator is flashing yellow, putting ourselves, and likely the U.S. Federal Reserve, on higher alert."
Investors had expected the Fed to stay on its tightening path after three hikes last year, but the ongoing trade war and recent disappointing corporate earnings have put those expectations to rest.
The December Fed funds contract imply a cash rate of 2.23 percent, below the current 2.25-2.50 percent and expectations of 3 percent just a couple of months ago.
Investors see rates at 2.00-2.25 percent by April next year.
"Markets have sharply re-priced the outlook for the Fed...with a rate cut 50 percent priced by December 2019 and fully priced by April 2020," said Tapas Strickland, markets strategist for National Australia Bank.
"Whether this pessimism continues for the rest of 2019 will largely depend on whether there is a near-term resolution to the trade war," Strickland added.
Concerns about a U.S. recession whacked Wall Street overnight, with the Dow skidding 2.8 percent, the S&P 500 down 2.5 percent and Nasdaq losing more than 3 percent.
MSCI's gauge of stocks across the globe shed 1.4 percent on Thursday.
Keeping with the risk-off theme, gold prices hit a 6-1/2-month peak of $1.294.88 an ounce.
Oil was on a slippery slope, with U.S. light crude off 42 cents at $46.67 a barrel but slightly above a 1-1/2 year trough of $42.36 touched just last month.
Reporting by Swati Pandey and Wayne Cole; Editing by Sam Holmes