* Spreadbetters expect European stocks to open lower
* MSCI Asia-Pacific index down 0.65 pct, Nikkei slips 0.35 pct
* N.Korea seen considering nuclear test in Pacific Ocean
* Gold rebounds, Treasury yield rise halts on safe-haven demand
* China stocks slip after S&P downgrades China's credit rating
* Oil hovers near 5-month high ahead of OPEC meeting
By Shinichi Saoshiro
TOKYO, Sept 22 (Reuters) - Asian stocks fell and the Japanese yen and Swiss franc gained on Friday after North Korea said it might test a hydrogen bomb in the Pacific Ocean and escalated a war of words with U.S. President Donald Trump.
Spreadbetters expected European stocks to start lower amid a chill in risk appetite, forecasting Britain's FTSE to open down 0.3 percent, Germany's DAX to open 0.2 percent and France's CAC to start 0.05 percent lower.
North Korean Foreign Minister Ri Yong Ho said on Friday he believes the North could consider a nuclear test on an "unprecedented scale" in the Pacific Ocean, South Korea's Yonhap news agency reported.
MSCI's broadest index of Asia-Pacific shares outside Japan handed back earlier gains and was down 0.7 percent.
The index rose to a decade high on Tuesday, lifted as Wall Street advanced to record levels, but fell back after the Fed heightened expectations for a third interest rate hike this year.
South Korea's KOSPI fell 0.9 percent on the latest bout of geopolitical tensions.
Australian stocks managed to advance 0.3 percent while Japan's Nikkei slipped 0.4 percent following a rise to a two-year high on Thursday.
"The headline about North Korea's nuclear test gave a little shock to the market," said Takuya Takahashi, a strategist at Daiwa Securities in Tokyo.
"Though the market is not expecting that there will be an immediate military action, it has triggered a profit-taking opportunity since the Nikkei had risen sharply recently."
Hong Kong's Hang Seng shed 0.8 percent and Shanghai was down 0.5 percent after S&P Global Ratings downgraded China's long-term sovereign credit rating on Thursday, less than a month ahead of one of the country's most sensitive political gatherings, citing increasing risks from its rapid debt build-up.
The dollar dropped 0.6 percent to 111.785 yen, pulling away from a two-month high of 112.725 touched on Thursday when U.S. yields spiked on the back of the Fed's hawkish stance.
The 10-year Treasury yield declined about 3 basis points to 2.251 percent as risk aversion favoured government bonds. It had risen for nine consecutive sessions prior, brushing a six-week high of 2.289 percent.
The Swiss franc rose 0.2 percent to 0.9687 franc per dollar . The yen and franc are often sought in time of broader risk aversion.
Safe-haven gold ticked up, with spot prices up 0.5 percent at $1,297.11 an ounce, after marking its lowest since Aug. 25 at $1,287.61 in the previous session on a firmer dollar.
Apart from geopolitical risks, the focus was on how the region's markets would fare when the Federal Reserve takes a step towards normalising monetary policy, as it projected on Wednesday following its policy meeting.
"It is difficult to pass a verdict on the Fed's stance until it actually starts its balance sheet reduction and the markets can gauge its effects," said Kota Hirayama, senior economist at SMBC Nikko Securities in Tokyo.
"Fundamentals continue to support emerging markets including those in Asia, although the Fed's latest stance did add a layer of uncertainty going forward."
In currencies, the Australian dollar was down 0.1 percent at $0.7926 after sliding 1.2 percent the previous day when Reserve Bank of Australia Governor Philip Lowe said the central bank does not have to follow a general move globally to raise interest rates.
A sharp drop in the price of iron ore, Australia's main export commodity, to a two-month low, has also weighed on the currency.
The New Zealand dollar was down 0.3 percent at $0.7284 on jitters ahead of a hotly-contested general election on Saturday.
The euro inched up 0.1 percent to $1.1954 and on track to end the week 0.8 percent lower.
The dollar index against a basket of six major currencies was down 0.2 percent at 92.052.
Crude oil prices were little changed amid a wait-and-see mood as ministers from the Organization of the Petroleum Exporting Countries, Russia and other producers meet later on Friday to discuss a possible extension of supply cuts.
Brent crude was down 0.1 percent at $56.39 a barrel after reaching a five-month high of $56.53 overnight.
Additional reporting by Ayai Tomisawa in Tokyo; Editing by Shri Navaratnam and Richard Pullin