US STOCKS-S&P 500, Dow set to extend longest losing spree in a year

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* U.S. coronavirus cases top 7 million

* Costco Wholesale drops on high COVID-19 costs

* Tech-related stocks set to climb again

* Futures: Dow off 0.37%, S&P down 0.25%, Nasdaq up 0.19% (Adds comments; updates prices)

Sept 25 (Reuters) - The S&P 500 and the Dow were to set to open lower on Friday, extending their longest losing spree in a year as fears about the outlook for the economy in a future still dominated by the coronavirus weighed on investor sentiment.

Shares of tech mega-caps including Facebook Inc, Alphabet Inc, Inc, Apple Inc and Netflix Inc, which are perceived as relatively safe assets at a time of economic uncertainty, inched higher in premarket trading.

A clutch of downbeat macroeconomic data has weighed on Wall Street in recent weeks, overshadowing signs of progress on Congressional stimulus that, analysts say, is needed to sustain an economic recovery.

“There’s evidence of a slowdown in the United States, which we think is temporary, but it would be reinforced if there is no additional fiscal package,” said Sebastien Galy, senior macro strategist at Nordea Asset Management in Luxembourg.

The benchmark S&P 500 is on course for its fourth straight weekly decline - its longest losing streak since August 2019 - and is hovering just above correction territory with investors oscillating between beaten-down technology-related shares and value-linked sectors such as industrials.

At 8:59 a.m. ET, Dow e-minis were down 100 points, or 0.37%, S&P 500 e-minis were down 8 points, or 0.25%, and Nasdaq 100 e-minis were up 20.75 points, or 0.19%.

Analysts warned the CBOE volatility index, known as Wall Street’s fear gauge, could climb higher toward the end of the quarter next week as well as the Nov. 3 presidential election.

Costco Wholesale Corp fell 1.7% as the warehouse chain recorded high coronavirus-related costs for the second straight quarter.

Boeing Co edged higher after Europe’s chief aviation safety regulator said the planemaker’s grounded 737 MAX could receive regulatory approval to resume flying in November and enter service by the end of the year.

Novavax Inc rose 5.5% after the drugmaker launched a late-stage trial of its experimental COVID-19 vaccine in the UK. (Reporting by Devik Jain in Bengaluru; Editing by Arun Koyyur)